Brief Information of the Compound and Protein
Compound Name
1-[(2R,3'R)-3'-(2-aminoethyl)-5-(2,5-difluorophenyl)spiro[1,3,4-thiadiazole-2,4'-2,3-dihydrochromene]-3-yl]ethanone
    Show/Hide
PubChem ID
CID: 58274714
Canonical SMILES
CC(=O)N1N=C(S[C@@]11[C@H](CCN)COc2ccccc12)c1cc(F)ccc1F
    Show/Hide
Compound Formula C20H19F2N3O2S
Compound Structure
Protein Name
Kinesin-like protein KIF11
Protein Classification
Other cytosolic protein
Uniprot ID
P52732
Gene Name
KIF11
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116 Homo sapiens (Human)  1
1
EC50 = 205 nM
   TI
   LI
   LO
   TS