Brief Information of the Compound and Protein
Compound Name
1-(4-fluorobutyl)-N-(4-methylcyclohexyl)-2-oxo-1,8-naphthyridine-3-carboxamide
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PubChem ID
CID: 118719599
Canonical SMILES
CC1CCC(CC1)NC(=O)c1cc2cccnc2n(CCCCF)c1=O
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Compound Formula C20H26FN3O2
Compound Structure
Protein Name
Cannabinoid receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Cannabinoid receptor
Uniprot ID
P34972
Gene Name
CNR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  2
1
EC50 = 20.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 21.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.35 nM
2 Ki = 1.36 nM