Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-methyl-N-(3-propan-2-ylphenyl)-3-[[3-(7H-purin-6-yl)pyridin-2-yl]amino]benzamide
    Show/Hide
 PubChem ID
CID: 73330894
Canonical SMILES
CC(C)c1cccc(NC(=O)c2ccc(C)c(Nc3ncccc3-c3ncnc4[nH]cnc34)c2)c1
    Show/Hide
Compound Formula C27H25N7O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 19.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.69 nM