Brief Information of the Compound and Protein
Compound Name
N-(3-cyanophenyl)-4-methyl-3-[[3-(7H-purin-6-yl)pyridin-2-yl]amino]benzamide
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PubChem ID
CID: 73331037
Canonical SMILES
Cc1ccc(cc1Nc1ncccc1-c1ncnc2[nH]cnc12)C(=O)Nc1cccc(c1)C#N
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Compound Formula C25H18N8O
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 29.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.717 nM