Brief Information of the Compound and Protein
Compound Name
 Compound Info 
12-[(2-acetylspiro[1,3-dihydroisoquinoline-4,1'-cyclopropane]-7-yl)amino]-7-(2-chlorophenyl)-2,5,7,11,13-pentazatricyclo[7.4.0.02,6]trideca-1(13),3,5,9,11-pentaen-8-one
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 PubChem ID
CID: 68193664
Canonical SMILES
CC(=O)N1Cc2cc(Nc3ncc4c(n3)n3ccnc3n(-c3ccccc3Cl)c4=O)ccc2C2(CC2)C1
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Compound Formula C27H22ClN7O2
Compound Structure
Protein Name
 Protein Info 
Wee1-like protein kinase
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase WEE family
Uniprot ID
P30291
Gene Name
WEE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000095 NCI-H1299
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 620 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.4 nM