Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(9R)-N-(diaminomethylidene)spiro[fluorene-9,2'-oxolane]-2-carboxamide
    Show/Hide
 PubChem ID
CID: 11536843
SID: 16638933
Canonical SMILES
NC(N)=NC(=O)c1ccc2-c3ccccc3[C@]3(CCCO3)c2c1
    Show/Hide
Compound Formula C18H17N3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 7
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P34969
Gene Name
HTR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
2
Ki = 5.1 nM
   TI
   LI
   LO
   TS