Brief Information of the Compound and Protein
Compound Name
N-(diaminomethylidene)spiro[fluorene-9,2'-oxolane]-2-carboxamide;hydrochloride
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PubChem ID
CID: 118717221
Canonical SMILES
Cl.NC(N)=NC(=O)c1ccc2-c3ccccc3C3(CCCO3)c2c1
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Compound Formula C18H18ClN3O2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 7
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P34969
Gene Name
HTR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
2
Ki = 1.7 nM
   TI
   LI
   LO
   TS