Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid
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 PubChem ID
CID: 60809
SID: 15222271
Canonical SMILES
CCCCCCOc1nsnc1C1=CCCN(C)C1
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Compound Formula C14H23N3OS
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000398 A-9
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 12.59 nM
   TI
   LI
   LO
   TS
2
Ki = 50.12 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 121 nM
   TI
   LI
   LO
   TS
2
IC50 = 316.23 nM
   TI
   LI
   LO
   TS
3
Ki = 8.128 nM
   TI
   LI
   LO
   TS
4
Ki = 11.75 nM
   TI
   LI
   LO
   TS
CL001014 CHO-CHRM2
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 398 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 120 nM
   TI
   LI
   LO
   TS
CL000845 CHO-K9
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  7
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
2
Ki = 213.8 nM
   TI
   LI
   LO
   TS
3
Ki = 269.15 nM
   TI
   LI
   LO
   TS
4
Ki = 275.42 nM
   TI
   LI
   LO
   TS
5
Ki = 323.59 nM
   TI
   LI
   LO
   TS
6
Ki = 380.19 nM
   TI
   LI
   LO
   TS
7
Ki = 724.44 nM
   TI
   LI
   LO
   TS