Brief Information of the Compound and Protein
Compound Name
(R)-8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol maleate
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PubChem ID
CID: 6440792
Canonical SMILES
CN1CCc2cc(Cl)c(O)cc2[C@@H](c2ccccc2)C1.O=C(O)/C=C\C(=O)O
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Compound Formula C21H22ClNO5
Compound Structure
Protein Name
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.22 nM
2 IC50 = 0.27 nM
3 Ki = 0.11 nM