Brief Information of the Compound and Protein
Compound Name
methyl 4-[[3-[8-(3,4-dimethoxyanilino)imidazo[1,2-a]pyrazin-6-yl]benzoyl]amino]benzoate
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PubChem ID
CID: 44187114
SID: 85182779
Canonical SMILES
COC(=O)c1ccc(NC(=O)c2cccc(c2)-c2cn3ccnc3c(Nc3ccc(OC)c(OC)c3)n2)cc1
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Compound Formula C29H25N5O5
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
EC50 = 293 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15.2 nM