Brief Information of the Compound and Protein
Compound Name
N-[3-[2-[[(1R,2S)-2-(4-chlorophenyl)cyclopropyl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
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Canonical SMILES
CCCN(CC[C@@]1(O)C[C@@H](C1)NC(=O)c1ccc2ccccc2c1)[C@@H]1C[C@H]1c1ccc(Cl)cc1
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Compound Formula C29H33ClN2O2
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2.8 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  2
1
ED50 > 100000 nM
   TI
   LI
   LO
   TS
2
IC50 = 327 nM
   TI
   LI
   LO
   TS