Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
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 PubChem ID
CID: 133633
SID: 16830225
Canonical SMILES
OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1
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Compound Formula C20H21ClN2O
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 90.4 nM
   TI
   LI
   LO
   TS
2
Ki = 60 nM
   TI
   LI
   LO
   TS
3
Ki = 87 nM
   TI
   LI
   LO
   TS
4
Ki = 100 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 48.6 nM
   TI
   LI
   LO
   TS
2
Ki = 104 nM
   TI
   LI
   LO
   TS
3
Ki = 163 nM
   TI
   LI
   LO
   TS