Brief Information of the Compound and Protein
Compound Name
4-[(1R)-1-[8-tert-butyl-2-(4-methoxyphenyl)-3-oxo-1,4-diazaspiro[4.5]dec-1-en-4-yl]-4,4-dimethylpentyl]-N-(2H-tetrazol-5-ylmethyl)benzamide
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Canonical SMILES
COc1ccc(cc1)C1=N[C@@]2(CC[C@@H](CC2)C(C)(C)C)N([C@H](CCC(C)(C)C)c2ccc(cc2)C(=O)NCc2nn[nH]n2)C1=O
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Compound Formula C35H47N7O3
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
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Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
2
IC50 = 360 nM
   TI
   LI
   LO
   TS