Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(R)-[8-tert-butyl-2-(3,5-dichlorophenyl)-3-oxo-1,4-diazaspiro[4.5]dec-1-en-4-yl]-cyclopropylmethyl]-N-(2H-tetrazol-5-ylmethyl)benzamide
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Canonical SMILES
CC(C)(C)[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](C1CC1)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1
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Compound Formula C31H35Cl2N7O2
Compound Structure
Protein Name
 Protein Info 
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
2
IC50 = 540 nM
   TI
   LI
   LO
   TS