Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R)-1-[4-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoro-1-phenylethyl)-3,4-dihydro-1H-isoquinoline-2-carboxamide
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 PubChem ID
CID: 90655360
Canonical SMILES
FC(F)(F)C(NC(=O)N1CCc2ccccc2[C@H]1c1ccc(cc1)C(F)(F)F)c1ccccc1
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Compound Formula C25H20F6N2O
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 168 nM
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   TS