Brief Information of the Compound and Protein
Compound Name
4,4-difluoro-N-(4-fluorophenyl)-1-[4-(trifluoromethyl)phenyl]-1,3-dihydroisoquinoline-2-carboxamide
    Show/Hide
PubChem ID
CID: 59536254
Canonical SMILES
Fc1ccc(NC(=O)N2CC(F)(F)c3ccccc3C2c2ccc(cc2)C(F)(F)F)cc1
    Show/Hide
Compound Formula C23H16F6N2O
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 548 nM
   TI
   LI
   LO
   TS