Brief Information of the Compound and Protein
Compound Name
(1R)-N-(3-cyanophenyl)-1-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide
    Show/Hide
PubChem ID
CID: 59536299
Canonical SMILES
FC(F)(F)c1ccc(cc1)[C@H]1N(CCc2ccccc12)C(=O)Nc1cccc(c1)C#N
    Show/Hide
Compound Formula C24H18F3N3O
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS