Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(8R)-N-(4-cyanophenyl)-8-[4-(trifluoromethyl)phenyl]-6,8-dihydro-5H-1,7-naphthyridine-7-carboxamide
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 PubChem ID
CID: 57625473
Canonical SMILES
FC(F)(F)c1ccc(cc1)[C@H]1N(CCc2cccnc12)C(=O)Nc1ccc(cc1)C#N
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Compound Formula C23H17F3N4O
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8R455
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS