Brief Information of the Compound and Protein
| Compound Name |
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
5-hydroxytryptamine receptor 2C
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Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
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| Uniprot ID | Gene Name | HTR2C |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | EC50 = 250 nM | ||
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| 2 | Ki = 2.884 nM | ||
| 3 | Ki = 4.8 nM | ||
| 4 | Ki = 5 nM | ||
| 5 | Ki = 5.012 nM | ||
| 6 | Ki = 10.47 nM | ||
| 7 | Ki = 13 nM | ||
| 8 | Ki = 15.85 nM | ||
| 9 | Ki = 17 nM | ||
| 10 | Ki = 21 nM | ||
| 11 | Ki = 23 nM | ||
| 12 | Ki = 24 nM | ||
| 13 | Ki = 100 nM | ||