Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[2-azaniumyl-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] hydrogen phosphate
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 PubChem ID
CID: 44398069
SID: 99431562
Canonical SMILES
CCCCCCCCc1ccc(CCC(N)(CO)COP(O)(O)=O)cc1
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Compound Formula C19H34NO5P
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
EDG receptor
Uniprot ID
Q99500
Gene Name
S1PR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
2
EC50 = 35.1 nM
   TI
   LI
   LO
   TS
3
EC50 = 44 nM
   TI
   LI
   LO
   TS
4
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.1 nM
   TI
   LI
   LO
   TS
CL000436 PathHunter CHO-K1 EDG1 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 97.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 2 nM
2 EC50 = 3.57 nM
3 EC50 = 13.6 nM