Brief Information of the Compound and Protein
Compound Name
N-{7-Cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]-carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}-cyclopropanecarboxamide
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PubChem ID
CID: 71627417
Canonical SMILES
N#Cc1c(Oc2ccc(F)c(NC(=O)Nc3cccc(C(F)(F)F)c3)c2)ccc2nc(NC(=O)C3CC3)sc12
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Compound Formula C26H17F4N5O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
IC50 = 22 nM
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