Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R)-2-(3-Fluoro-4-(5-methyl-1H-imidazol-2-yl)-phenyl)-N-hydroxy-3-phenylcyclopropanecarboxamide
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PubChem ID
CID: 60148950
SID: 144077001
Canonical SMILES
Cc1cnc(-c2ccc([C@H]3[C@H](C(=O)NO)[C@@H]3c3ccccc3)cc2F)[nH]1
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Compound Formula C20H18FN3O2
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1 Homo sapiens (Human)  2
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 60 nM