Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R)-2-[3-(5-fluoropyrimidin-2-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
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PubChem ID
CID: 60148712
SID: 144076746
Canonical SMILES
ONC(=O)[C@@H]1[C@@H]([C@H]1c1cccc(c1)-c1ncc(F)cn1)c1ccccc1
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Compound Formula C20H16FN3O2
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1 Homo sapiens (Human)  2
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100 nM