Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R)-2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-hydroxy-3-phenylcyclopropanecarboxamide
    Show/Hide
PubChem ID
CID: 60148648
SID: 144076667
Canonical SMILES
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc2c(c1)OCCO2
    Show/Hide
Compound Formula C18H17NO4
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1 Homo sapiens (Human)  2
1
IC50 = 620 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM