Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9765054, Compound 28G
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 PubChem ID
CID: 60148672
SID: 144076697
Canonical SMILES
ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccnc(c1)C(F)(F)F)c1ccccc1
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Compound Formula C16H13F3N2O2
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 300 nM