Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9765054, Compound 50i
    Show/Hide
 PubChem ID
CID: 60148736
SID: 144076770
Canonical SMILES
ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1cncnc1)c1ccccc1
    Show/Hide
Compound Formula C20H17N3O2
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 100 nM