Brief Information of the Compound and Protein
Compound Name
(-)-Pramipexole
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PubChem ID
CID: 119570
SID: 14748917
Canonical SMILES
CCCN[C@H]1CCc2nc(N)sc2C1
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Compound Formula C10H17N3S
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P61169
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  2
1
EC50 = 21.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 450 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 39 nM