Brief Information of the Compound and Protein
| Compound Name |
2-(4,4-difluoropiperidin-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Histone-lysine N-methyltransferase EHMT2
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Protein Classification |
Epigenetic regulator
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Protein methyltransferase
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| Uniprot ID | Gene Name | EHMT2 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 < 2.5 nM | ||
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| 2 | IC50 = 220 nM | ||
| 3 | Kd = 230 nM | ||
| 4 | Ki = 3.7 nM | ||