Brief Information of the Compound and Protein
Compound Name
6-fluoro-5-[2-[4-[2-[4-(tetrazol-1-yl)phenyl]acetyl]piperazin-1-yl]ethyl]-3H-2-benzofuran-1-one
    Show/Hide
PubChem ID
CID: 72376019
Canonical SMILES
Fc1cc2C(=O)OCc2cc1CCN1CCN(CC1)C(=O)Cc1ccc(cc1)-n1cnnn1
    Show/Hide
Compound Formula C23H23FN6O3
Compound Structure
Protein Name
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS