Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(5-(2,6-Dimethoxy-phenyl)-1-{4-[(3-dimethylamino-propyl)-methyl-carbamoyl]-2-isopropyl-phenyl}-1H-pyrazole-3-carbonyl)-amino]-adamantane-2-carboxylic acid hydrochloride
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 PubChem ID
CID: 9940110
SID: 14913316
Canonical SMILES
COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)C3CC4CC(C3)CC2C4)nn1-c1ccc(C(=O)N(C)CCCN(C)C)cc1C(C)C.Cl
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Compound Formula C39H52ClN5O6
Compound Structure
Protein Name
 Protein Info 
Neurotensin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Neurotensin receptor
Uniprot ID
P30989
Gene Name
NTSR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 10000 nM
   TI
   LI
   LO
   TS
2
EC50 > 80000 nM
   TI
   LI
   LO
   TS
3
IC50 = 50.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.24 nM