Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-hydroxy-4-({4-[5-(2-methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoyl}amino)benzoic acid
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 PubChem ID
CID: 2286812
Canonical SMILES
C\C(\C=C1/SC(=S)N(CCCC(=O)Nc2ccc(C(O)=O)c(O)c2)C1=O)=C/c1ccccc1
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Compound Formula C24H22N2O5S2
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 522 nM
   TI
   LI
   LO
   TS
2
Ki = 8.76 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
2
IC50 = 2361 nM
   TI
   LI
   LO
   TS