Brief Information of the Compound and Protein
Compound Name
2-[4-[4-(4-amino-8,8-dimethyl-5-oxo-7H-pyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]acetic acid
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Canonical SMILES
CC1(C)CN(c2ccc(cc2)[C@H]2CC[C@H](CC(O)=O)CC2)C(=O)c2c(N)ncnc2O1
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Compound Formula C23H28N4O4
Compound Structure
Protein Name
Diacylglycerol O-acyltransferase 1
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O75907
Gene Name
DGAT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 146 nM
   TI
   LI
   LO
   TS