Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[4-[4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6-yl)phenyl]cyclohexyl]propanoic acid
    Show/Hide
Canonical SMILES
Nc1ncnc2OCCN(c3ccc(cc3)[C@H]3CC[C@H](CCC(O)=O)CC3)C(=O)c12
    Show/Hide
Compound Formula C22H26N4O4
Compound Structure
Protein Name
 Protein Info 
Diacylglycerol O-acyltransferase 1
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O75907
Gene Name
DGAT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 131 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 31.62 nM