Brief Information of the Compound and Protein
Compound Name
N-[5-(2-tert-butylpyridin-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1-carboxamide
    Show/Hide
PubChem ID
CID: 71682653
Canonical SMILES
Cc1nc(NC(=O)N2CCCC2)sc1-c1ccnc(c1)C(C)(C)C
    Show/Hide
Compound Formula C18H24N4OS
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 620 nM