Brief Information of the Compound and Protein
Compound Name
(2S)-1-N-[4-chloro-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
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PubChem ID
CID: 59293721
Canonical SMILES
CC(C)(c1cc(ccn1)-c1sc(NC(=O)N2CCC[C@H]2C(N)=O)nc1Cl)C(F)(F)F
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Compound Formula C18H19ClF3N5O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O00329
Gene Name
PIK3CD
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 4900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 430 nM