Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazino]ethoxy]ethanol
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 PubChem ID
CID: 54742459
SID: 15474461
Canonical SMILES
OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
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Compound Formula C23H16O6
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 50 nM
   TI
   LI
   LO
   TS
2
EC50 = 1200 nM
   TI
   LI
   LO
   TS
3
Ki = 11.5 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
2
EC50 = 500 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 500 nM
   TI
   LI
   LO
   TS
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 2.1 nM