Brief Information of the Compound and Protein
Compound Name
 Compound Info 
SID50106181
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 PubChem ID
CID: 3014059
Canonical SMILES
C[N+]1(C)CCC(OC(=O)C(c2ccccc2)c2ccccc2)CC1.[I-]
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Compound Formula C21H26INO2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P20309
Gene Name
CHRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
IC50 = 0.31 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.41 nM
   TI
   LI
   LO
   TS
3
Ki = 0.22 nM
   TI
   LI
   LO
   TS
4
Ki = 0.44 nM
   TI
   LI
   LO
   TS
5
Ki = 0.68 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 5.1 nM
   TI
   LI
   LO
   TS
2
Ki = 2.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.43 nM
2 IC50 = 0.56 nM
3 IC50 = 0.59 nM
4 IC50 = 1.9 nM
5 IC50 = 2.6 nM
6 Ki = 0.4 nM
7 Ki = 0.42 nM
8 Ki = 0.4467 nM