Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)-yohimbine
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 PubChem ID
CID: 8969
SID: 14754428
Canonical SMILES
COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12
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Compound Formula C21H26N2O3
Compound Structure
Protein Name
 Protein Info 
Alpha-2A adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P08913
Gene Name
ADRA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.42 nM
   TI
   LI
   LO
   TS
2
Ki = 3.13 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 8.4 nM
   TI
   LI
   LO
   TS
2
Ki = 3.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.4 nM
2 Ki = 3.1 nM