Brief Information of the Compound and Protein
Compound Name
 Compound Info 
FOSTAMATINIB
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 PubChem ID
CID: 11671467
SID: 125299332
Canonical SMILES
COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)N(COP(O)(O)=O)c4n3)n2)cc(OC)c1OC
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Compound Formula C23H26FN6O9P
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 267 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17 nM
2 IC50 = 12000 nM