Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(2-Methoxyethyl)-4-(6-(pyrimidin-5-yl)quinazolin-2-ylamino)benzamide
    Show/Hide
 PubChem ID
CID: 71584540
SID: 163636686
Canonical SMILES
COCCNC(=O)c1ccc(Nc2ncc3cc(-c4cncnc4)ccc3n2)cc1
    Show/Hide
Compound Formula C22H20N6O2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6400 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 777 nM
   TI
   LI
   LO
   TS