Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-Pyridin-4-yl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-quinazolin-2-amine
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 PubChem ID
CID: 71582942
SID: 163634797
Canonical SMILES
c1cc(-c2ccc3nc(Nc4ccc(OCCN5CCCC5)cc4)ncc3c2)ccn1
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Compound Formula C25H25N5O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 101 nM
   TI
   LI
   LO
   TS