Brief Information of the Compound and Protein
Compound Name
N-(3-(5-(2-aminopyrimidin-4-yl)-2-tert-butylthiazol-4-yl)phenyl)-2,5-difluorobenzenesulfonamide
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PubChem ID
CID: 57989722
Canonical SMILES
CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2)c(-c2ccnc(N)n2)s1
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Compound Formula C23H21F2N5O2S2
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000313 SK-MEL-28 Homo sapiens (Human)  1
1
IC50 = 7 nM
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