Brief Information of the Compound and Protein
Compound Name
2,6-difluoro-N-(2-fluoro-5-(2-isopropyl-5-(2-(2-(methylsulfonyl)ethylamino)pyrimidin-4-yl)thiazol-4-yl)phenyl)benzenesulfonamide
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PubChem ID
CID: 57989790
Canonical SMILES
CC(C)c1nc(-c2ccc(F)c(NS(=O)(=O)c3c(F)cccc3F)c2)c(-c2ccnc(NCCS(C)(=O)=O)n2)s1
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Compound Formula C25H24F3N5O4S3
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000313 SK-MEL-28 Homo sapiens (Human)  1
1
IC50 = 51 nM
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