Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-3,3,3-trifluoro-2-[2-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonyl-1,3-thiazol-5-yl]-2-hydroxypropanamide
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 PubChem ID
CID: 49846545
SID: 104174724
Canonical SMILES
C[C@@H]1CN(CCN1S(=O)(=O)c1ncc(s1)[C@](O)(C(N)=O)C(F)(F)F)c1ccc(F)cc1C(F)(F)F
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Compound Formula C18H17F7N4O4S2
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 145 nM
   TI
   LI
   LO
   TS