Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-8-oxa-3-azabicyclo[3.2.1]octane
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 PubChem ID
CID: 46244883
SID: 96106922
Canonical SMILES
CS(=O)(=O)C1(CC1)c1cc(nc(n1)-c1cccc2[nH]ccc12)N1CC2CCC(C1)O2
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Compound Formula C22H24N4O3S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase ATR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13535
Gene Name
ATR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
2
IC50 = 350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM