Brief Information of the Compound and Protein
Compound Name
N-[5-[(2-acetamido-[1,3]thiazolo[5,4-b]pyridin-5-yl)-methylamino]-2-fluorophenyl]-3-(2-cyanopropan-2-yloxy)benzamide
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PubChem ID
CID: 71450431
SID: 163443214
Canonical SMILES
CN(c1ccc(F)c(NC(=O)c2cccc(OC(C)(C)C#N)c2)c1)c1ccc2nc(NC(C)=O)sc2n1
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Compound Formula C26H23FN6O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
IC50 = 30 nM
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