Brief Information of the Compound and Protein
Compound Name
8-chloro-7-[4-(5-fluoro-2-methoxyphenyl)piperidin-1-yl]-3-(2,2,2-trifluoroethyl)-[1,2,4]triazolo[4,3-a]pyridine
    Show/Hide
PubChem ID
CID: 57459497
SID: 163456173
Canonical SMILES
COc1ccc(F)cc1C1CCN(CC1)c1ccn2c(CC(F)(F)F)nnc2c1Cl
    Show/Hide
Compound Formula C20H19ClF4N4O
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 10.5 nM
   TI
   LI
   LO
   TS