Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(4-cyano-2-fluorophenoxy)methyl]-2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]pyrazole-3-carbonitrile
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 PubChem ID
CID: 67633261
Canonical SMILES
CCc1cnc(nc1)N1CCC(CC1)n1ncc(COc2ccc(cc2F)C#N)c1C#N
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Compound Formula C23H22FN7O
Compound Structure
Protein Name
 Protein Info 
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q8TDV5
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2.78 nM
   TI
   LI
   LO
   TS
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 5.36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 9.25 nM