Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(3R)-3-[2-(4-methylpiperazin-1-yl)ethoxy]pyrrolidin-1-yl]-N-[4-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]sulfanylphenyl]acetamide
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 PubChem ID
CID: 53340226
SID: 125005151
Canonical SMILES
CN1CCN(CCO[C@@H]2CCN(CC(=O)Nc3ccc(Sc4nc(Nc5cc(C)[nH]n5)c5cccn5n4)cc3)C2)CC1
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Compound Formula C29H38N10O2S
Compound Structure
Protein Name
 Protein Info 
Aurora kinase B
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
Q96GD4
Gene Name
AURKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000067 HCT 116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 169 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 2.9 nM