Brief Information of the Compound and Protein
Compound Name
(S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)-butyl]-thiophene-2-carbonyl}-amino)-pentanedioicAcid
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PubChem ID
CID: 135567028
SID: 96032811
Canonical SMILES
Nc1nc2[nH]c(CCCCc3ccc(s3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1
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Compound Formula C20H23N5O6S
Compound Structure
Protein Name
Trifunctional purine biosynthetic protein adenosine-3
Protein Classification
Enzyme
>
Ligase
Uniprot ID
P22102
Gene Name
GART
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000423 IGROV-1 Homo sapiens (Human)  1
1
IC50 = 3.46 nM
   TI
   LI
   LO
   TS
CL000220 KB Homo sapiens (Human)  2
1
IC50 = 3.13 nM
   TI
   LI
   LO
   TS
2
IC50 = 630 nM
   TI
   LI
   LO
   TS